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nullmouse

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Posts posted by nullmouse

  1. Medical science right now will be viewed as barbaric in a couple of hundred years time as drilling holes in the skull was during medieval times, basically we cut parts out and zap tumours with a bit of radiation. It's still basically the same butchery that went on in those times, just refined with a better understanding of how, but as destructive.

    What is known, as proven though placebo AND other means is that the human mind is more powerful than the medicine in a lot of ways, you genuinely believe you are gonna get through cancer, have a supportive environement, the chances are, you will pull through, you give up, get depressed, you're gonna die.

    I'm sure it's not the way you intended this to read, but part of what you've said here is potentially very misleading. First, I'll agree that the current methods for treating cancer are fairly nasty, but it's a nasty disease that has a nasty pathology that can, in most tumours, recurr and spread with ease - It's also a disease that carries a substantial risk of death. Part of my research interests include ways to prevent people from developing cancer to reduce the number of people that have to face the unpleasant reality of chemotherapy/radiotherapy/surgery.

    However, and you'll understand why I need to be clear on this, these therapies are used because they are effective and proven to be so. Just having a happy disposition will not cure someone of cancer and, although I'm sure it's not what you meant to say, the suggestion that someone can dispense with proven medical treatments and survive could be fatal advice.

    BUT, lets get into the more out there thoughts, I've said nothing new to any of you probably. Let's really get into the human psyche. Ever heard of the hallucinogen Ibogaine? It's trips take people on a road to self healing, and you know what, it's being tested out in London right now, by medical doctors to cure addiction in heroin addicts, it's a powerful trip and it shows you to yourself. After one trip many are reported never to touch heroin/coke/tobacco again. Just google "ibogaine treatment" and you'll find many many sites.

    So, how is this in any way different to the shaman in the jungle drinking his ayahausca? Is it at all?

    :D

    I'm not familiar with the literature on this drug with regards to its effectiveness, but irregardless there's nothing to say that a medical cure can't be found from nature and used as an effective treatment: The difference between the drug ibogaine and the shaman's ayahausca would be the purity and regulated potency of the drug. Many modern medicines (including some of the vinca alkaloids used in cancer chemotherapy) are based on naturally occurring compounds that have been purified and often chemically modified to make them more effective.

    Like any medicine, the claims that ibogaine can help people recover from addiction can be tested - But in this case there would be many, many confounding factors and limitations to do so. For example, how could you design a placebo control for a study using a psychoactive agent? Or how could you prove you weren't subtituting one person's addiction for another? How could you prove that any benefits were due to a self-awareness trip and not some other pharmacological effect of the drug?

    The idea of using a potent hallucinogen as a therapy for addiction seems counter-intuitive, and would probably create another set of problems such as drug-drug interactions, dependency, mental health concerns and so forth. Maybe there is call for drastic measures in drastic situations (a psychological analogy to the butchery of cancer therapy, perhaps?), but I would personally expect to see a large volume of realiable, well-performed research to back that up. How feasible that is given some of the factors above is a matter for debate.

  2. Ace. Does anyone know if this is likely to sell out and where I'd buy tickets if I have to get them in advance?

    ps. hi. Newish to Aberdeen, new to the forum(posting at least). Don't rip me for my dodgy taste in music ;)

    You'll be fine paying at the door, but I'll take a note of your username and make sure if it does sell out on the door that you'll have a space reserved!

    (I agree with Lucky Rathen, and Nick Cave fan status buys you privileges too!)

  3. Japanese psyborgs PSYDOLL return from the workshop, having spent the last couple of years since their last UK tour perfecting and recording the new album "10 Spyglasses". Digital percussionist Uenoyama and guitar-robot Ucchi join forces with keytar-wielding vocalist Nekoi to create punked-up industrial rock wizzed through a manga blender. Post-apocalyptic calls-to-arms and cautionary fairytales, all through the eyes of a confused, half-organic/half-robotic bunch of crazies. Magic stuff. Like Bladerunner gone a bit 'wrong'.

    Welcome to PSYDOLL Official WebSite

    Psydoll on MySpace Music - Free Streaming MP3s, Pictures & Music Downloads

    Edinburgh-based trio METALTECH speedball industrial and dance, dressing it all up in slick grease-paint, dayglo gasmasks and inflatable femme fatales. Plenty here for fans of The Prodigy, KMFDM, Skinny Puppy, Rob Zombie and the ilk.

    MetalTech on MySpace Music - Free Streaming MP3s, Pictures & Music Downloads

    Monday the 2nd of November

    Drummonds, Aberdeen.

    8pm / 5

    Support from Metaltech + TBC

    They're also playing Edinburgh and Glasgow:

    Thursday the 5th of November

    Voodoo Rooms, Edinburgh.

    9pm / 4 or 3 with NUS ID.

    Support from Metaltech

    Friday the 6th of November

    13th Note, Glasgow

    9pm / 4

    Support from The Paraffins plus TBC

  4. Last Harbour - Dead fires and the lonely spark (worth a listen if you like My Latest Novel or The Bookhouse Boys)

    The Twilight Sad - Forget the night ahead (so far so good, on the first listen!)

    Daniel Johnston - Is and always was (alright, needs another listen or two I think)

    Ulrich Schnauss - A strangely isolated place (awesome)

    Venetian Snares - Filth (nae too sure about the song titles, but solidly crazy)

  5. I've got 4 or 5 albums and I love them all. Great band live, Colin is a great front man, very entertaining. Hazards of Love would be a bad place to start, but it is a good progression for them as a band.

    Apparently the current live set is the entirety of Hazards of Love followed by a 'greatest hits' stylee hour-odd encore. Pity they're only playing London.

  6. I do so love The Decemberists. The new album, The Hazards of Love, is a veritable rock opera - something I'd normally balk at - but it's marvellous and I'm unashamedly addicted to it.

    For my money, they'll have to go a long way to beat The Mariner's Revenge Song from Picaresque (

    - not the original video), but most stuff they release is gold.
  7. Open question to anyone really: Wouldn't sticking needles in your body result in an increase in adrenaline production giving you a more elated feeling and lessening the affects of any other "problems" that you were having at all? Could explain why people feel that that sort of thing works. *shrugs*

    There are alternative theories for how acupuncture may work, that don't rely on the antiquated view of meridians and qi flow. One of which is known as the "gate control" theory of pain, which suggests that acupuncture may overload the body's ability to deal with pain and shuts the 'gate' that controls it. It's similar to your suggestion, in that it could be a physiological mechanism of action, but it's not proven. Again, we could test this hypothesis by using needles that don't penetrate the skin: Fake needles that apply pressure that feels like being pierced, but actually just retract into a sheath that sticks to the surface of the skin have been developed. If penetration (fnar) is required, then these fake needles should have no effect or the real needles should do substantially better.

    (Except, of course, there'd be no way of preventing the acupunturist from knowing if they had real of fake needles - it would be obvious they had fake needles, so they could consciously or subconsciously effect the results. Gah, these things are called "confounding factors" and they're a pain to control for.)

  8. I've had a brief look through the last few pages, and I think there's a few issues floating around (hurrah for comedic understatement). There seems to be some misconceptions about the nature of scientific evidence (absence of proof does not mean absence of research, for example) and some discussion on whether a treatment being a placebo or not really matters. Luckily, Sense About Science have produced a really, really nice little brochure precisely about these issues and it's applicable to not just alternative therapies but any treatment.

    You can read it here: http://www.senseaboutscience.org.uk/pdf/I've%20got%20nothing%20to%20lose%20by%20trying%20it%20FINAL.pdf

    It explains in nice detail how we gather data for evidence based medicine, addresses the issue of whether doing something is better than nothing and also provides some really good links for those of you passionate about the direction this thread has taken.

  9. If the NHS are practicing acupuncture then it must have some scientific value!TCM is not just about acupuncture.My practitioner has a degree in physics and is a very intelligent man,if he can't help you,he won't take money off you for the sake of it.

    TCM isn't just about acupuncture, true - But it's a good example that fits in with the rest of the thread. Irregardless, any TCM should be subject to the same scrutiny as any medical treatment in order to ascertain its effectiveness.

    The NHS stance on acupunture is a controversial one, and is based on evidence that doesn't necessarily show that acupuncture is any better than a fake needling session. What the evidence does show is that doing acupuncture is better than doing nothing for some conditions. The key question is if acupuncture actually does anything that random needle placing wouldn't. For the treatments that the NHS prescribe acupuncture for, that it is not yet known.

    I can't really comment on your practitioner, from what you say he sounds like a nice guy though.

  10. Would these trials be on anything like the scale of the trials for the various NRT treatments though? I somehow doubt it. Personally, I believe that acupuncture for addiction issues brings a largely psychological benefit, a true placebo effect, so these results don't surprise me. I'd be more interested in trials concerning ME if you've got any info on that.

    Anyway, I'm not really arguing with anything you've posted in this thread as you've obviously got a balanced view.

    A lot of these trials do fall short of having the same numbers as you'd expect from a properly controlled trial, which is why organisations like the Cochrane Library give them less weight when reviewing the available evidence. The more robustly designed trials (of which numerous do exist), are given more weight. Given the breadth of conditions acupuncture is suggested to treat it's not surprising that some of the evidence may get spread a little thin, but it's certainly not non-existent. I'm all for big, carefully controlled experiments for every treatment whatever the outcome, but they're not always practical to perform for a wide range of reasons (cost often being the major one, to be honest).

    With regards ME, there's currently a report being compiled by the Cochrane library (the font of all evidence-based medicine fun) on the effectiveness of acupuncture for the alleviation of chronic fatigue syndrome. Unfortunately, that means there's no conclusion to share just now, but here's something I did find from a recent journal review:

    Studies on the treatment of chronic fatigue syndrome (CFS) with acupuncture and moxibustion in China were reviewed. All studies concluded the treatments were effective, with response rates ranging from 78.95% to 100%. However, the qualities of the studies were generally poor, and none of them used a RCT design. The common acupoints/sites used in the treatment of CFS, which may reflect the collective experience of acupuncturists in China based on Traditional Chinese Medicine theories can be used to evaluate the effectiveness of acupuncture for the treatment of CFS in future studies using more scientifically rigorous study designs.

    Note that this review only looks at studies from China (who may have a national pride stake in acupuncture working) and none adhered to an RCT design (meaning patients were neither randomly assigned into groups or controlled appropriately). The authors reflect this in their conclusions. Note though, that the reported success rate in these studies is "78.95% to 100%". The old rule of thumb about "if something sounds too good to be true, it probably is" springs to mind - But keeping an objective mind, this would appear superficially promising. To be 100% sure, proper studies would need to be performed that both randomised the patients in to groups and made sure half of them received fake treatment. If, under those conditions, they still got such high success then everyone would be on to a winner. At the moment, all the studies they review are just comparing doing something to doing nothing, which can't tell us if the treatment is anything more than placebo...

  11. Medical Establishment: This is a load of hooey as there is no hard evidence to back up the claims of TCM practioners.

    TCM Practitioners: Wanna do some studies?

    Medical Establishment: No.

    I'd disagree, as many, many studies have been done upon a wide range of alternative therapies. As an example, here's the summary of the Cochrane report on the use of acupuncture as a means of helping people quit smoking (Spoiler: It doesn't):

    We identified 24 reports of studies. The only comparison for which there were sufficient studies to combine meaningfully was acupuncture compared with sham acupuncture. The fixed-effect odds ratio (OR) for the short-term effect was 1.36 (95% confidence interval 1.07 to 1.72), but the studies are heterogeneous and the result is strongly influenced by one individual positive study. The significant short-term effect was lost with the random-effects model for pooling, or by removing the outlying study that led to heterogeneity. The long-term result shows no effect of acupuncture compared with sham acupuncture. There was no consistent evidence that acupuncture is superior to no treatment, and no evidence that the effect of acupuncture was different from that of other anti-smoking interventions, or that any particular acupuncture technique is superior to other techniques.

    For that particular, specialised application of acupuncture they found 24 studies that have attempted to answer this particular question. Note, not all of the studies found were performed properly (which is a big problem), but this illustrates that studies are prevelent, are being performed by researchers and are also being analysed in some detail: It's not just a case of dismissively waving it away with a hand, and nor should it be. Again, these claims can and are being evaluated.

  12. Yes but surely the evidence of it being accurate from a diagnostic sense,then the treatment speaks for its self.TCM has evolved to what it is now,acupuncture is available on the NHS.My physio uses it to stimulate blood flow.I get what you are saying,but it has worked for me and my wife so i can only comment from a personal point of view.

    I think the important thing is that every treatment (alternative or not) is properly evaluated for how effective it is, otherwise anyone could claim anything and no-one would be able to refute it.

    The availability of acupuncture on the NHS is limited to specific treatments and is part based on successful political lobbying (hello, Prince Charles), part based on the available data suggesting it may be more effective than simply doing nothing. The jury is still out whether acupuncture works as claimed, or is just a special version of the placebo effect: In either case, doing something is better than doing nothing, but the latter calls in to question the method by which acupuncture supposedly works. One argument would be that as long as it's better doing something rather than nothing, then it doesn't matter if acupuncture works due to meridians and qi flow or if it works as nothing but a placebo. A counter-argument to this would be that if acupuncture is just a placebo, then it is not a treatment with any efficacy and to claim it is would be deceitful.

  13. I really don't get your logic or how you arrived to that conclusion,but it it is your opinion,which i respect!Totally agree Nullmouse,it's a pity Western medecine and TCM couldn't work as complementary treatments eh?

    I agree with The TickingTime-Bomb as the more recent the evidence the more likely it is to be carried out to the highest scientific standards. For example, our understanding of the placebo effect and how it can impact poorly controlled trials is relatively recent to medicine - Older trials will most likely be subject to inappropriate controls that make it hard to work out what is a true effect and what is placebo.

    Just to be clear, I don't think we should recommend any treatment without evidence. That evidence should be gathered in the strongest, most robust way - But the ways in which we gather this evidence does not rely on the need to know the mechanism why a treatment works. For example, acupuncture is claimed to work due to insertion of needles into certain regions (meridians) that are specific to the ailments presented. We don't need to know how (or indeed, if) meridians work to understand that a good control would be to insert needles in to regions that weren't specific. We could then compare how well the two groups did, and make some observation on how effective the treatment was.

  14. Absolutely,the evidence for TCM is thousands of years old,funny how when you tell a doctor or consultant about TCM they look at you with a raised eyebrow.

    Well, you have to look at the quality of the evidence: When I talk about evidence-based medicine I'm pretty much referring to the way in which current clinical data is gathered via carefully controlled trials. The thousands of years evidence for TCM is pretty much all anecdotal evidence, testimonials and such. This isn't to say that there can't be truth in these testimonials, but they're not scientific evidence.

    If any TCM treatments work, then they can be tested used the principles of evidence-based medicine (proper controls, randomised groups, 'blinding' so patients and doctors don't know what treatment they're giving etc) and solid evidence gained without needing to understand the mechanism behind the effect.

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