Reason is not a good choice as you cannot record audio.
Cubase + a sound card - and there are millions to choose from - would be a good combination. There's a new cut-down version of Cubase just out. For the sound card think about how many mics you want to record at once, whether or not they need phantom power, and how you're going to play back what you're recording. That should help narrow down which card is suitable.
Hope that helps!
Steven
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