[HairyScaryMark]

Out of the pedals you listed the ME20 is probably the best but you really would be better getting individual pedals as it gives you more flexibililty and generally higher quality.

I have Native Instruments Guitar Rig and I use it regularly just would never concider using it live. There really is no point and real amps sound better (well, the good ones do anyway). I have had Guitar Rig crash a number of times also (usually I was running other audio software at the time however). The quality of the effects is also not that great. Always feel a bit let down by their reverb and chorus and I don't really like the interface that much.

Also, what do you want multi effects for? To make whale noises?

Just get yourself a decent reverb and distortion pedal. Maybe add a bit of chorus and delay if you want a bit more excitment.

Speaking from experience. I've bought novelty items of gear before and always wish I had just got a decent (small) amp and a few pedals.